Genital herpes is an STD caused by HSV-1 or HSV-2, although, genital herpes is mostly caused by HSV-2. Genital herpes is a contagious viral infection affecting primarily the genitals of men and women. Genital herpes is characterized by recurrent clusters of vesicles and lesions at the genital areas or below the waist. A person usually gets HSV-2 infection during sexual contact with someone who has a genital HSV-2 infection.